ADME-Enabling Technologies in Drug Design and Development - download pdf or read online

By Donglu Zhang,Sekhar Surapaneni

A complete consultant to state of the art instruments in ADME research

The final decade has noticeable large growth within the improvement of analytical strategies akin to mass spectrometry and molecular biology instruments, leading to very important advances in drug discovery, quite within the quarter of absorption, distribution, metabolism, and excretion (ADME).

ADME-Enabling applied sciences in Drug layout and improvement makes a speciality of the present cutting-edge within the box, providing a complete evaluate of the newest instruments for producing ADME info in drug discovery. It examines the broadest attainable diversity of obtainable applied sciences, giving readers the knowledge they should select the proper device for a given program, a key needful for acquiring favorable ends up in a well timed model for regulatory filings. With over thirty contributed chapters through a global crew of specialists, the ebook provides:

  • A thorough exam of present instruments, protecting either electronic/mechanical applied sciences and biologically established ones

  • Coverage of functions for every expertise, together with key parameters, optimum stipulations for meant effects, protocols, and case studies

  • Detailed dialogue of rising instruments and strategies, from stem cells and genetically transformed animal versions to imaging technologies

  • Numerous figures and diagrams through the text

Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical technological know-how will locate ADME-Enabling applied sciences in Drug layout and improvement a useful consultant to the whole drug improvement approach, from discovery to regulatory issues.

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ADME-Enabling Technologies in Drug Design and Development by Donglu Zhang,Sekhar Surapaneni


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